My r7000 groupset has no rub in any gears. I can trim the small-small to not rub. I easily can ride the big-big and no rub at all. Naturally this is considered cross chaining and most road bikes can be set up to no have any rub. I am a mechanic that probably helps and I take my time to get everything dialed in but chain rub can be taken out of the equation with proper set up. On my disk bike with r7000 I can ride in the 50-34 gear no rub.