I have gotten some numbness in the past and I have tried a few saddles, but the best advice is a micro-adjust seatpost.

I’m using a Suntour XC Pro on my road bike; although there are others out there.

Once you find a saddle that seems to be the best, and the fore/aft is where you want it, then (at least for me) it is just a matter of dialing in the tilt.

Being able to make slight adjustments on a ride seems to be the best way to approach in real time.

John