While not popular among roadies, I switched to SPD pedals on my road bike years ago and haven't looked back. I always hated walking like a duck when wearing Look-style SPD SL style cleats and shoes. Modern carbon sole shoes are so stiff, one doesn't notice or feel what pedal is attached (i.e., no "hot spots"). The only downside to using SPD pedals is likely the weight of the shoe and pedal combination, but if one isn't racing, it doesn't matter.