Originally Posted by
jonwvara
Yes, that can work, but as you point out, you'll still have the limited chain wrap of a short-cage derailleur. The critical thing is to make sure that your chain is long enough to handle the big-big combination. That's a cross-chained gear you don't ordinarily use, but there's a very good chance that you will someday shift onto it by mistake. If and when that happens with a too-short chain, you're going to break something, and maybe hurt yourself, as I learned the hard way many years ago. (I know already know this, ehoplex, but I mention it here for the benefit of those who may not.)
This is how I always set mine up. Enough chain for any eventuality and avoid those where I have too much chain, which is logical anyway.