Two more notes:
I had a 60cm hybrid bike that fit well with seat/handlebars in a low configuration. It was a good fit until I cracked the aluminum head tube.
I also had a 50cm Crosscut that never did fit well, despite trying several combinations of seat, stem, and bars. It was just...too...small to get the job done well. I could get the seat high enough (barely), but the bars were too close, and I had issues with toe strikes and heel strikes (when using the rear rack). There's a reason I don't have that bike anymore.