The problem is the number of speeds. If you stuff a wheel in there, you will most likely flare the dropouts and the hanger won’t be straight. If you are going to run friction shifting, it probably won’t matter.

If you are jumping to 9-10-11 speed index it will probably have issues. Most threads where there are shifting problems will have at least one is the hanger bent response. I can’t imagine not having a hanger issue if you don’t cold set and align the dropouts.

John