Yes. Should be a straight swap. Had a GRX 810 (40t) put on my '19 Sirrus X carbon last year to replace the heavy no-name stock one. The latter was probably the same as yours. No issues at all.
I'd get a new Shimano b/b while you are at it (in fact, I believe you might have to). I used the Ultegra one (BBR60), threaded external cups for 68mm (or 70mm) shell. You could also use the 'Tiagra' one (BBRS501).