Mine just might take larger than 2.0. But that looks plenty big enough for me for on-highway, and even then, standard mudguards would not fit, I'd need to rig something non-standard. Around town, I've been running no guards, had to pull them off to fit first set of 1.75s (though those were deep treaded). It would be mostly for a tour I'd want guards, as on a long one, likely to hit some rain, and also a long flap in front might also help keep dust and coastal salt off the drivetrain in the dry.