Originally Posted by
Leisesturm
Recent posters are...ignoring the cage length necessary to wrap large ranges between big and small cogs. You cannot use a short cage (or even medium) to shift 11-50T! ...
You need to update your knowledge to the state of the conversation in 2024. I have myself built and used a 11-46T cogset with a
medium cage GS derailer (part
Shimano Deore RD-M6000-GS, 10-speed) while having no less than 5cm of ground clearance on a 20"(406) wheel.
It works perfectly, shifting smoothly, crisply and quickly across the entire cogset, affording 21-86GI with a 47T chainring. It's actually quite amazing how well it works. I would not hesitate to recommend it.

Shimano Deore RD-M6000-GS
Now, as for 50T max cog, there are videos on YouTube and on this forum channel which I have shared showing two other Shimano
medium-cage RD that can span with a 11-51T cogset with varying success. Those parts are, in addition to the one listed above:
- Shimano SLX RD-M7000-GS, 11-speed
- Shimano XT RD-M8000-GS, 11-speed
The point here is that you ought not be so categorically dismissive that it could work in the face of practical evidence that it can work.
Shimano XT RD-M8000-GS rated for 46T max cog

11-46T cogset for the
Shimano XT RD-M8000-GS part
Shimano SLX RD-M7000-GS, 11-speed
Finally there is a Microshift medium-cage RD, Reddleman will know which one, that can span at least 48T max cog.
.
.
Incidentally, a short-cage SS derailer like the
Shimano Zee RD-M640-SS part can span a 11-42T cogset.
The trick in all instances, short- or medium-cage, is to finesse the chain length.