That is mostly the short and long of it. While my experience has been 1x, I have learned the following: If you are gonna go really big on chainring and cassette, use the steel wolftooth. I experimented, years ago, with an 11-50 and a forgotten, but large-ish chain ring. Worked for a while, but on a simple, up hill, non-stressed shift from third to second, something went wrong and the aluminum goat link sheared off and the derailleur arm wound up in the spokes. What really happened, I don't know: exceeding the Altus derailleur by way too much; cheap link, other act of f.o.d.? Currently I still run an aluminum link, BUT I only exceed my derailleur a little. An old Deore with a 42/11-42 setup.

My other possible contribution is backing up the chain wrap caution. 7 speed, 50/11-34, Acera derailleur. Very happy setup, but could be better on hills. Having an MTB double, a spare 28 tooth chainring, hilly roads, and getting a trailer, I set a manual shift arrangement in the 64bcd position. When on the "towing" ring, the chain (after link adjustment) maxes out the wrap ability of the derailleur. On the other end, the 50/34 arrangement (same chain) works safely and fine but can't stand any more links out. So, in the future (and if I want lower gears for towing) I will have to reduce the 50 chainring as I reduce the 28.

Has anyone mentioned the possibility of using a longer B screw?

Otoh, experiment, do what you would like, and let us know what you find out.