If you can get one with GRX 2X 11-speed gearing, get a 46/30T crank and 11-40T XT or SLX cassette. It works. I have this on my Soma Saga touring bike with cable shifting, and my all-road bike, with Di2. Both use the GRX 2X rear derailleur officially rated for 11-34T. A B-screw adjustment is all I needed to use the 40T cassette. I could probably have gone with 42T.