I've been using sealant for the last three years on my road/gravel bike, my wife's ebike, her road bike, and much longer on my mountain bike.

I am not sure I have had any punctures on any of these, but probability suggests there have probably been a few that nobody noticed. We use Orange Seal endurance and top it off about every 4 months. Sometimes I have had to pick a little bit of sealant out of a valve when I am topping it off.

Overall, it is FAR less work*. Otherwise, I would not bother.


* Full disclosure: setting them up can be a PITA.