Thread: Creatine
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Old 10-09-24 | 07:24 PM
  #44  
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Originally Posted by MoAlpha
From my reading, the cause of DOMS is still unknown and the micro-tear hypothesis of muscle hypertrophy and strengthening seems to have less and less support. Micro tearing occurs, but does not seem to be necessary for the response. No time to pull literature now. Maybe later.

It seems to be the H+ ion associated with lactate that stimulates pain muscle pain receptors during exercise.
Thanks. I found this over on Quora: "The real cause of sore muscles, hours and days after extreme exercise, is the influx of fluids, prostaglandins, and white bloods cells, to the muscle area in an effort to repair the damaged tissue." Like you say. I wonder how this produces nerve signals, but I wonder about a lot of things. HMB, which reduces muscle soreness, rather than speeding muscle repair seems to reduce muscle breakdown in the first place, which fits.
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