At your height, head tube length or stack height is going to be critical to getting a comfortable fit on the long rides. Get the tallest you can find. I would prioritize that over the claimed reach, stem length will let you modify that part a bit. Even at my "average" height, I have longer arms and legs with short torso that usually puts me on a bigger road frame than expected. I still use the same cockpit length as I did 20 years ago, but I shop frames with a higher stack now. Makes getting bars up easier when you don't have to go in search of special ugly stems and steerer extenders.

More tire clearance is always a good thing. You can put skinnier tires on for fast rides, but frames with no clearance take away options.