Originally Posted by
big john

Lidl-Trek was using this set up at Paris Roubaix. A TPU tube as a liner for a makeshift run flat system. Also, lots of 35mm tires were seen and even XTR rear derailleurs.
Watched a video where the mechanic was recommending buying TPU tubes, with removable valve caps, for tubeless tires. The logic was that when it was time to replace the tire, there would be no mess and that in the event of a puncture, the sealant would still work. Interesting concept with a small weight penalty - but there are always trade offs for convenience.