I love my Domane, but got it used and am not sure I'd pay new bike prices for a new one.
Is Canyon off the table for you? You could get the bike delivered right to your door with minimal setup. The CF series would get you a carbon frame and electronic shifting for less that $3,500 (before taxes). I've never owned a Canyon, but it seems like those that do own them are happy with them.
https://www.canyon.com/en-us/road-bi...n-product-grid