I and my friends have a couple of Trail Blaze builds.
It has a standard BSA 68mm BB and a 142 thru axle rear O.L.D., so when using wide tire (>2.0), the chain may interfere with it. One of solutions is to consider a wider crank.
And regarding the cassette, I don't think 50t will fit, because you can only use short or middle cage RD.

Your bike looks great GTA and thanks for the wider crank suggestion. Was thinking about thudbuster or similar but might go for a dropper post instead as they help with my dodgy balance