Ok, we may be getting somewhere. I was 270 when I started and had the same problems between two dif bikes/same saddle. I think you are having problems relating to down pressure because you're a big guy. The pain inside the upper thigh/hamstring is a charlie-horse, yes? This is caused by almost subliminally trying to get off the saddle!

Q: Are you at or near your target/comfort weight?
Asking because if you are losing weight, who knows where you will end up in a few months. I went through a few saddles as I lost 45 pounds. Ended up on a Brooks B-67. I lost the lard but the bones don't change position - they're still wider than average, thus, the -67.

If you're already at your comfort weight, we start from there. Big guys need big saddles. Unfortunately, the market doesn't offer much in the way of quality for the big guys. What I found was mostly gel-junk or some type of padding that caused heat build-up and chafing. The other end of the spectrum was expensive, but too narrow, racing/road types.

I have to suggest a Brooks at this point - and a big one, like mine. At about $85 you can spend alot more on others, believe me. I think you need springs and the subtle 'give' of thick hide. I think you can benefit from the slickness of polished leather which will alleviate hotspots and chafing while breaking it in. At 270, it won't take but 150 miles or so. It was that way with me.

Bottom line is, (no pun) that setup is killing your enjoyment. You may be looking at a different saddle for each bike, Brooks or no.

So, another Q: What Brooks did you hate so much? You definitely don't fit the bill for a Pro or even a B-17. At 170mm, the 17 is quite narrow. The 67 is 230mm. You've probably seen my pics but if you want, I'll post them again.