Having gone out this morning for a couple of hours, I tried saddle adjustment using the following method:

Make a change (saddle tilt, height, or fore-aft, but only one)
Ride 10 or 15 minutes - better or worse?
If worse, reverse adjustment & try another. If better, leave adjustment & try another.

What I found after 9 or 10 adjustments, was that my saddle was significantly farther back and lower than what the LBS had determined as "most efficient" fit. The ride is almost comfortable now (using the Specialized Milano on the Klein Navigator frame).

I wonder if this has something to do with my body geometry? I'm bow-legged and flat-footed and my feet angle out at the toes. When the LBS fits, they insist on having my feet soles-flat-on-the-pedals and parallel to the plane of the frame. This isn't "normal" riding geometry for me since my feet normally contact the pedals only on the outside of the platform.

In any case, I'll continue to experiment. Something's got to work...