I would pay more for a handmade from if and only if it was also custom fitted to my specific measurements. For example, I can fit on almost any bike and be able to ride it, however, if I had a load of cash to blow, I go to a custom frame builder and have them make a specific frame designed to fit my short legs/long torsoe, clydesdale self!
L8R
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"Life is not a journey to the grave with the intention of arriving safely in a pretty and well preserved body, but rather to skid in broadside, thoroughly used up, totally worn out, and loudly proclaiming, "WOW, What a Ride!" - unknown
"Your Bike Sucks" - Sky Yaeger