"Try lowering your seat enough that the weight is on your...seat...not your wrists?"

I don't think it's that easy. If I lower my seat two things happen...knee pain and my gut will be even more in the way of my legs than they are now. I think I need to have my bike fitted for me. I have heard different LBS's use different techniques (some eye ball it...some have fancy equipment) any ideas on which is best? I'm not sure that my riding position is optimal right now.