i ride a track bike (not road track) with deep track drops and steep drop between saddle and bars, on a selle italia SLR saddle. i can take this bike out for 40-50 mile rides and stay relatively comfortable. i don't think that the frame itself has much to do with my comfort level, however. it's all about the bars and the saddle. if i were to go on 100 mile rides, i'd probably consider switching to bullhorns and a terry fly saddle, and raising the bars a bit.