Yes you can. It won't hurt the paint or vinyl decals. If there are already rust bubbles under the paint go ahead and break them open so the acid can get to the rust. Use a no-scratch pad from time to time on the worst spots while the frame is soaking. Don't forget to pickup some heavy duty rubber gloves while shopping in the paint department.

When you're finished with the acid bath, blow dry the frame thoroughly then spray it inside and out with a metal protector. I use Amsoil HD Metal Protector.

Once you are ready to touch-up or paint the outside of the frame, wipe it down thoroughly with a Wax and Grease remover first, then wax the frame after the paint has dried.