Yeah, I think if the hub is rated for radial, it's ok at full tension. I wouldn't undertension a rear wheel just so I could lace radially with a shimano hub. Rear wheel tension is too valuable.

Personally, I think it's a much better design to lace radial on the drive side. If you do that, you give the drive side spokes a better angle of approach to the rim, so the non-drive spokes will have to be higher tension to compensate. This works to even the tension between the left and right sides.

Conversely, if you radially lace the non-drive side, you give the non-drive spokes the pulling advantage, so they will need to be at an even lower tension, which worsens the tension differential.

I think radial drive and 3x non-drive is a great design if you've got a hub that supports it.