There are so many factors to balance. What temps do you want in the winter? How much rain? Access to beaches? Mountains? Large Cities? High Density population? Medium? Low? Do you care about the political climate? Cost of Living? Crime Rate? Access to the Arts? Sports? Beautiful scenery? Forests? Do you speak Spanish? Do you want to Fish? Surf? Hunt? Raft? How important is closeness to family?

Answers to these and dozens of other questions will guide your choice.

I've been to the Charleston and liked it a lot. Can be kinda expensive. Nice moderate temps. I love the old historic section.

I would love to have a split arrangement, north in the summer, south in the winter.