I attended spinning classes for many years before taking to the road in ernest. I always road with lycra and nothing else. Road cycling, at first, over 40 miles started to hurt a little on my stock saddle. Got a new saddle that fits my butt, bought the Pearl Izumi Race pad shorts with 11 mm of pad designed for long time in the saddle and it is all good now. Road a century in the new shorts and at the end it was happy cheeks all the way. Nothing else required so far.