Funny... back in the day some (okay, it was buycycling mag) recommended Noxema, and there was a photo of Andy Hampsten loading his (leather?) chamois. My experience was not so great. Seemed like it actually softened your skin, or maybe the eucalyptus or whatever just made it more sensitive. Plus, poor staying power. And to top it off, in a paceline, well, it smells like Noxema. After several hours, kind of like a mint with BO. Probably decent antibacterial, but I find cleaning quickly and thoroughly after to be pretty effective.