I like mine tilted down just a little bit. One of the first things i noticed about this saddle is that it tries to "throw" you forward. I first thought that was a negative. I have since learned that it is better to have the weight off of my bum and onto other parts of the body, mainly the legs. The centrifical force manufactured by pedaling supports a lot of this weight.
This position allows only for the sit bones to hit the seat, nothing else (important stuff) is in free space.