you shouldn't have a problem with 48x16, but I guess it depends what terrain you are used to. The altitude can take a bit of getting used to, you will feel sluggish until you get soem riding time down.
I ride a 49x16 or 46x15 which are pretty much the same. mos tof my friends have similiar gearing, and some have it a bit easier.
Let me know when you get here if you want to be informed about the races going on.