To prepare, I posted a message asking for cycling advice in Spokane, and I got some great help and suggestions from local Spokane riders. See the thread at
http://www.bikeforums.net/showthread.php?t=49201.
Packing the bike at home as a single took about 90 minutes, because it was the first time I packed it for travel in its case. I went slowly, watched the video that came with the bike, and cleaned grease and dirt off the bike as I packed it. I had extra room, so I packed my cycling shoes and all the tools for the bike in the case as well. My helmet and cycling clothes went into my second bag that I checked in separately.
At the airport, the only surprise was that the bike case weighed in at 49.5 lbs. For my Horizon flight to Spokane (two prop), I had missed the weight limit by only .5 lb. Ugh.
Here's a pic of what the case looks like: