As far as driling goes a good cobalt tipped or full cobalt bit will work with lots of cutting fluid (or WD-40 can be used as a good cutting fluid) As far as tapping goes get a few taps in the size you want tap the hole first with one then again with another as Ti is hard on taps and drill bits made for steel. There are special coatings they use for facing and BB taps for ti that makes them almost useless for aluminum or steel because they cut to fast in those materials. I have drilled in Ti a few times with no problem as long as you get a good bit. I drilled out some odesey Ti axle pegs from 3/8 to 14mm. Did 4 pegs with one bit and it was still cutting good. It was also a 30 dollar bit