I've noticed that during my warm-up phase, using a light gear brings on a sharp pain in my knee... as soon as I flip down to a higher gear and the load increases- the pain goes away almost instantly.....
Once I'm warmed up its another story, I just want to push it as much as possible......
Ohh well.
I am using a 9spd rear and a double front with a 52 or 53 big ring.