I've found that about 2 weeks of riding gets my butt to conform to the requirements of riding. Thats pretty much 5 solid rides (20 mi) during each week. After which the pain is gone.
If you let a bunch of days lapse between rides - like 3 or 4 days - then you'll be starting from square one again
Just the way it goes...
There is no amount of padding or saddle design that will alleviate that 'adjustment' period, sorry.
Nothing you can wear, nothing you can do position-wise.
The 2nd thru 4th days of riding are the worst, and if you stretch out the time between rides you'll be doomed to relive 'Groundhog Day' of butt ache over and over again.
Actually, most riders will find that large amounts of padding only prolong the agony and in fact will cause serious numbing 'down there'. Bunching of padding and fabric only add to the agony.
I loathe being the 'messenger' of this, but the upside is if you tough it through and get some miles under your keester in a regular way, it'll get better fairly quickly.
BTW, on cycling goals, I always try to take small bites - a solid 40 miler before a metric century (60 mi) before a full bore 100... that leaves a lot to look forward to