Originally Posted by sam21fire
All of the cargo compartments of commercial planes flying in the US are pressurized, as well as the cargo compartments of commercial shippers (UPS etc). Remember that people check their dogs etc and they go in with the rest of the baggage. Another thing to remember is that the airplane's tire are pressurized and don't seem to explode in flight (normally!).
Sam
The weight of the plane relieves pressure on the tire when the plane takes off. Plus airplane tires are much larger than bicycle tires. A slight change in size would be meaningless for the airplane but
could be disaster to a high pressure bicycle tire.