You shouldn't have any trouble with those Axial Pros unless you make a habit of running through broken glass, or falling into pot holes and other kinds of debris.
I've got over a thousand miles on mine with no problems. As stated above you need to stay relaxed, without panic, if you should get a flat.
For peace of mind you might consider a tire liner that goes between the tube and the casing. I, personally, don't think you need them, but you have to be the judge.