There are too many variables to make a sweeping statement. If a wheel gets its light weight from fewer spokes and/or a shallower rim, it will be weaker. If it gets its light weight from carbon fiber, then it can be quite strong.
Some components are stronger and lighter, like double-butted spokes. Then you have to consider AL nipples, rim tape vs. hole covers, and tubular vs. clincher.
Then there's the whole hub thing. The lowest rolling resistance hubs are also the most durable -- and heaviest (loose ball Campy and Shimano).
If you're looking for durable wheels, I don't recommend you buy any wheel with a name. To me, "durable" would mean 20k-30k miles. Get them built and have the builder select appropriate parts for you, your routes, and riding style. You can build a 32h wheel (very strong) for less money and less weight than most $1000 boutique wheelsets.
Race wheels are for race day. Of course only the really fast racers save them for race day (pros). I've had many friends come to me with spokes breaking or cracks around the spoke holes from 2-year-old (or less) boutique wheels, while my handbuilts keep rolling.