Originally Posted by zephyr16

the quick release wouldnt have enough power to hold your rear hub in place, as with fixed gears the forces exerted are greater and can be in both directions. this isnt the case with singlespeeds, qr's can be used w/ horizontal drops no problem.

i doubt you would have a problem if you went with a reasonable gear ratio and you ran a brake and never skidded. but still, dont do it. people will laugh and you will look silly.