Thats debatable. I've been using the thorn resistant tubes and I regularly run them at 115-120 psi on my 700x23's and the only time I've encountered rough riding is when the road itselft is rough. They are slightly heavier though but nothing a little gearing doesn't fix.

I guess I favor them because they cost considerably less than good tires and the only time you will really have a flat is if you encounter goat heads, nails, and other lengthy puncturing objects. You know, things that good puncture resistant tires can't defend from either.