Get to a podiatrist.

I've got a Morton's neuroma, which an enlarged nerve that usually occurs in the third interspace, which is between the third and fourth toes. I got fitted for an orthodic that has a pad that basically pushes the interspace apart, thus alleviating the pressure on the nerve.

I don't ride with my orthodic, but do wear cycling shoes with a very wide front, so the pressure isn't too bad, even for century rides. The stiff sole on a cycling shoe will be more comfortable and your feet will not fatigue like with a running shoe, which is built to pad and flex.

Makes sure your everyday shoes are not pinching your forefoot. Tight shoes are a killer for a neuroma.

And get to a podiatrist!