I have the Chrome Metro, Reload Deluxe,and a Baileyworks Courier 253 (it was my birthday...really). The Deluxe is truly massive though not as big as a Chrome Kremlin (had that too). My quick opinions:

Metro is the best fitting for on the bike comfort - don't need the stabilizer strap really, that's how well it fits one me. Can adjust with one hand and the split-strap buckle design is good for getting it off in a hurry. The organizer pockets started to annoy me cuz they are 'flat' so it's kind of hard to get your hand in there. Can't wear it off one shoulder for off bike walking so I switched to the Reload. Kind of gets uncomfortable when it is stuffed. Good size for everyday stuff like clothes, books. Waterproof.

Reload is heavy even when empty. Will fit a ton of crap. So much that I end up throwing everything and then some in. Strap is very stiff so adjusting it on the bike requires riding no-hands. The Deluxe has compression straps which is a godsend when the bag is not full. I bought this bag with the intention of using it as an everyday commuting, air travel carry-on, diaper/kid bag and while it works for those purposes I am finding that I want a slightly smaller bag for most days. I like that it hangs off one shoulder comfortably for when I walk around town. Fairly stable on the bike without the stabilizer strap (I rarely use that strap) but still slowly migrates around sometimes.

The Baileyworks medium 253 Courier is currently the most used bag right now. I can't believe how well it works given the smaller size and the simple strap system. Carries a lot more stuff than it looks like it would. Stable on the bike without the stabilizer strap (have not used this strap yet). Even stuffed, it carries just fine. Can carry off one shoulder comfortably so it is great for just walking around too.

The Reload was pricey. The Chrome was the cheapest (got it used). The Baileyworks was reasonably priced. The Metro is smaller than the Courier. If you do go with the Courier, you might want to consider getting pockets to organize things. I find things get lost inside that cavernous cargo area. If you are not worried about wearing it off the bike go with the Metro. I might be selling mine soon.