My Flyte cyclocross bike has toe overlap, (12'' shoes size) but only 1/4'' with 28c tires. Yes, I can deal with it, but... I hopped on my wife's Cannondale ST700 Silk Tour bike and it was nice to have no overlap at all with 700x38c tires. Maybe since I'm coming from a mountain bike background my riding style is different and it matters more.