I work in Pt Loma...

B&L on east side of Camino del Rio South - right at the Rosecrans exit off I5 or I8. It's a Specialized Concept Store. I'm not impressed with that store's clothing selection (Solana Beach is MUCH better).

Performance Bike Shop on Midway about a mile north of Rosecrans i nthe Vons Shopping Center. There is also a Sports Chalet in the same center that has a small selection of cycling jerseys (usually Canari).

Moment Cycle Sport farther down on Rosecrans (near Shelter Island Dr), but it's a small triathlon-oriented shop with not very much variety of clothing in stock.