Hopefully if you're really a "Runner", then your knees would be slightly stronger than to allow a simple twist to practically cripple you....

Something don't sound right here.... Either you don't "run" much or your knees are terribly out of shape, which is impossible if you actually are a "Runner"...

Get the picture?

"Seely" does have a good point though...Seat height definitely does have an effect on both your pedal power & the amount of strain on your legs, including the knees....