My first compact was a Ritchey Logic. It had the 110mm spider but came with a 53/38. When I lived in Michigan, I put on a 42. When I moved to Utah, the 38 left me huffing on the big long steep climbs so I put some FSA 50/34s on and it worked fine.

I think that your solution will be to be swapping chainrings and or cassettes based on the riding scenario that you will be faced with. Not a big deal, I use to swap cassettes all the time in less time than it takes to change a tire. I would suggest that you stick with a medium to longish cage on your rear derailure to accommodate chain wrap for the variable range that you are talking about.