Originally Posted by Little Darwin

OK... Ignoring chain tension etc, and using numbers easy to calculate...

Drive side 48 x 12, a 4:1 ratio

Reverse side 48 x 24 a 2:1 ratio

Pedalling at 100 rpm forward would on the drive side give you a rear wheel speed of 400 rpm.

With the rear wheel spinning at 400 rpm, the non-drive side would work like a typical geared bike rolling backwards, so the spinning wheel would move the cranks.

At a 2:1 ratio, this would attempt to move the cranks at 200 rpm.

Typical cranks can not turn 100 rpm on one side, and 200 rpm on the other, so it will not work, unless the gearing on both sides is identical... which is not what was suggested.

This configuration will not work.

THAT is my final answer.