Lots of potential places to go here in the states. A nice bottle of single malt would really make me open up. ;-)

How much time are you going to have? How many miles? Hilly? Flat? Somewhere in between? What about your budget and time of year?

I live in the deep south where we have all sorts of terrain, but the weather can be brutal in the summer if you're not accustomed to it. But on the other hand, we have lots and lots of rural roads with little traffic. Cost of touring here in the south is also quite reasonable.