I got Ergon grips because I was having wrist pain, and I haven't had it since. Occasionally I do get pain in my palm, but so far it's been only occasional and hasn't lasted long.

So I'm not sure whether to recommend them or not. I'm a big fan of mine, but my problem was different from yours. If you have an REI or another store with an accommodating return policy nearby, you could always try them for a week or two and see if it makes a difference.