The one thing you should never do is run or ride away. If the ML sees you running from it, it will activate its predator prey instinct and it will come after you. Make yourself as big as possible, possibly holding your bike up in front of you and slowly walk towards the ML. This will usually scare it off. If it does attack you, do not play dead like they tell you to with a bear. Try to fight it off with anything you have sticks, rocks, or try and gouge its eyes out. Just out of curiousity where is this mountain lion at in Missouri.