1. Make sure your saddle height and fore/aft positions are correct.
Some tips can be found at
http://www.sbraweb.org/setup.htm
and
http://www.peterwhitecycles.com/fitting.htm
2. Make sure you are not trying to push too high of a gear.
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"Let us hope our weapons are never needed --but do not forget what the common people knew when they demanded the Bill of Rights: An armed citizenry is the first defense, the best defense, and the final defense against tyranny. If guns are outlawed, only the government will have guns. Only the police, the secret police, the military, the hired servants of our rulers. Only the government -- and a few outlaws. I intend to be among the outlaws" - Edward Abbey