I got an entry level Peugeot racing bike in the mid 80's and then in the mid 90's pretty much stopped riding it entirely after I got a mountain bike.
About 3 years ago I got the Peugeot out again and it felt really strange. Part of it was a new seat that a person I had borrowed it to had put on and part of it was because I had to readjust the seat height, handle bars, etc. Most of it however was just that it was so different from what I had become used to riding.
Last spring I started riding it almost exclusively to train for a triathlon my family had talked me into doing. Before long I was again very comfortable on it although it took a while longer to get adept at using downtube shifters. Now, I prefer a road bike and even after riding the MTB during the winter, I found it very easy to go back to a road bike again this spring.